BI 7271

CAS No. 1883429-34-2

BI 7271 ( BI 7271 )

Catalog No. M12929 CAS No. 1883429-34-2

BI 7271 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BI 7271
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 7271 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.
  • Description
    BI 7271 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9; displays >1,000 fold selectivity over the bromodomains of BRD4; suppresses the proliferation of AML cells.
  • Synonyms
    BI 7271
  • Pathway
    Chromatin/Epigenetic
  • Target
    Bromodomain
  • Recptor
    Bromodomain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1883429-34-2
  • Formula Weight
    352.43
  • Molecular Formula
    C21H24N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methylisoquinolin-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hohmann AF, et al. Nat Chem Biol. 2016 Sep;12(9):672-9.
2. Pérez-Salvia M, et al. Epigenetics. 2017 May 4;12(5):323-339.
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